Personnel

The EQAPOL program is led by Thomas N. Denny, Professor of Medicine, Chief Operating Officer of the Duke Human Vaccine Institute (DHVI) and Principal Investigator of the EQAPOL Central Laboratory- the Immunology and Virology Quality Assessment Center (IVQAC). Each EQAPOL program component is managed by the following investigators at Duke University, with support provided by external collaborators as indicated below:

  • Ambrosia Garcia maintains the Peripheral Blood Mononuclear Cell (PBMC) cell bank and reagent repository.
  • Guido Ferrari leads an enzyme-linked immunosorbent spot (ELISpot) assay External Quality Assurance (EQA) program.
  • Kent Weinhold leads an EQA program for flow cytometry-based assays, with support from Becton Dickinson.
  • Feng Gao (molecular characterization), Todd DeMarco, and Heidi Register (viral cultures) lead the effort to establish and characterize unique clade-specific HIV virus panels, with support from Blood Systems Research Institute (Michael Busch).
  • Michael Busch, BSRI, and the EQAPOL team are working with the CDC to develop and launch an HIV-1 Incidence Assay EQA Program.
  • Greg Sempowski leads the Luminex EQA program.
  • Paul Debien and SciMed Solutions, Inc. have created a central web database for the above activities.

All EQAPOL components are being developed to operate using Good Clinical Laboratory Practices (GLCP) whenever possible. In addition, the ELISpot, Flow Cytometry, and Luminex EQA Programs are A2LA Accredited for ISO/IEC 17043 (certificate no. 3614.01). This effort is being directed by the Central Quality Assurance Unit (CQAU), which is led by Marcella Sarzotti-Kelsoe.

The EQAPOL programs are further supported by the EQAPOL Program Managers, Andrea Pappas and Chris Todd, and Program Coordinator, Kristen Gunnell while statistical support is provided by DHVI Biostatisticians Wes Rountree and Marek Poniewierski. Administrative, financial, regulatory and facilities support is provided by established departments within DHVI.